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Lymphomation.org > Tests & Imaging

"No Test is Perfect" below

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Last update: 08/19/2014

Diagnostic
 

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Overview of how lymphoma is diagnosed
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Biopsy  

FNA | IGCNB

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Bone Marrow Biopsy

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Flow Cytometry  

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FISH Panel

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Histology

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Immuno-cytochemistry

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Kappa / Lambda Ratio

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Lumbar Puncture

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LymphoChip

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Mediastinoscopy

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PCR testing for
Minimal Residual Disease (MRD)
- updated 

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Splenectomy

Imaging

Surveillance controversy

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About & Comparing

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Bone Scan

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CT Imaging

Risks of CT


Medical Imaging: Safety Resources
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Gallium scan

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Lymphangiogram

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MRI 

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PET scan

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SPECT

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Ultrasound 

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Ultrasound Endoscopy

Labs

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About Blood Tests

CBC | CRP | WBC

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Disease direction Indicators

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Immunoglobulins

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LDH

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Human beta-2 M

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H-pylori

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T-cells

Other

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DiSC Assay

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Doppler

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Endoscopy

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Epstein-Barr virus

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MUGA scan
(Cardiac function)

Also see Molecular Diagnostic Tests - surgery.wustl.edu

 

Every Test for Lymphoma has limitations!

For example, how sensitive PET is at picking up a cluster of malignant cells depends on the type of cancer (aggressive versus indolent) but also how many cells exist in the area imaged. A single cell is far too small to be detected, even dozens of cells. But a large lesion that is negative suggests a non-malignant cause. So yes, there are false-negative tests, but it’s certainly a favorable sign when negative.

So imaging tests are not diagnostic, and blood tests rarely so … Only a biopsy can determine if the cells in the sample taken are a cancer and what type– and even with a biopsy the finding is limited to the cells that are sampled.

What's New:

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Your Test Results and HIPAA - rules and tips
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Labtests Online: understanding lab tests

 

PCR Testing  moved here


 
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SV40 virus tests?  Our understanding is that there is no reliable standard blood test for the virus. PCR testing of tissue stored at biopsy may be used, however. See SV40 for updates.

 

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SPECT Scan

"Similar to PET, single photon emission computed tomography (SPECT) uses radioactive tracers 
and a scanner to record data that a computer constructs into two- or three-dimensional images." 

See http://imaging.cancer.gov

 

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Free Kappa and Lambda Light Chains Plus Ratio

B-cell carries either kappa- or lambda-light chains on its surface (a distinctive marker). 

Normal, polyclonal B-cells are a mixture of kappa-B-cells and lambda-B-cells (one marker or the other)
 
When malignant B-cell clone proliferates it will lead to b-cell population consisting 
of either only kappa- or only lambda-B-cells.  (one marker, and not the other, suggests malignancy)

Adapted from med4you. 



 

 
Disclaimer:  The information on Lymphomation.org is not intended to be a substitute for 
professional medical advice or to replace your relationship with a physician.
For all medical concerns,  you should always consult your doctor. 
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