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Side Effects > Metabolic abnormalities in lymphoma

Last update: 08/22/2010

Introduction | Resources & Research News

Many lymphoma patients report leg cramping following treatment. Here we list metabolic abnormalities in lymphoma patients undergoing chemotherapy, and links to resources.
 
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The following was adapted from:  Metabolic abnormalities in lymphoma. 
Clin Lymphoma. 2002 Dec;3 Suppl 1:S32-6. PMID: 12521387  PubMed 

Tumor lysis syndrome can result in several metabolic abnormalities, leading to potential renal failure. If these syndromes are identified promptly, they can be corrected.  

Chemotherapy- and lymphoma-associated
metabolic abnormalities include:

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Electrolyte Imbalance, Chemocare.com http://bit.ly/9BTMfm
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Low Potassium, (Hypokalemia) Medicinenet.com  http://www.medicinenet.com/low_potassium_hypokalemia/article.htm

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Hyperuricemia - high uric acid levels
Details: www.emedicine.com/med/topic1112.htm 

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Hypercalcemia - high concentrations of calcium compounds are found in the bloodstream.
Details: www.emedicine.com/EMERG/topic260.htm 
A Practical Approach to Hypercalcemia www.aafp.org/afp/20030501/1959.html 

See also Vitamin D caution
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Hyperphosphatemia - high concentration of phosphates in the circulating blood. 
Details: www.emedicine.com/emerg/topic266.htm 

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Hypocalcemia - abnormally low calcium concentration, that can result in muscle cramps, abdominal cramps, spasms, and hyperactive deep tendon reflexes. 
Details: www.emedicine.com/EMERG/topic271.htm 
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Hypomagnesemia - abnormally low levels of serum mangnesium. "The primary clinical findings are neuromuscular irritability, CNS hyperexcitability, and cardiac arrhythmias."
Details: www.emedicine.com/EMERG/topic274.htm 
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Hyponatremia - abnormally low levels of serum sodium concentration.
Details: www.emedicine.com/EMERG/topic275.htm 
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Hyperkalemia - a potassium level greater than 5.5 mEq/L. Ranges are as follows: 5.5 - 6.0 mEq/L - Mild condition 6.1 - 7.0 mEq/L - Moderate condition 7.0 mEq/L and greater - Severe condition. Details:  www.emedicine.com/emerg/topic261.htm 
   

Related Resources & Research News

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Electrolyte imbalance
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Metabolic emergencies in the cancer patient. Semin Oncol. 2000 Jun;27(3):322-34. Review.
PMID: 10864220  PubMed
 
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professional medical advice or to replace your relationship with a physician.
For all medical concerns,  you should always consult your doctor. 
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